Human ZHX1 activation kit by CRISPRa

CAT#: GA107746

ZHX1 CRISPRa kit - CRISPR gene activation of human zinc fingers and homeoboxes 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ZHX1
• Locus ID: 11244
• Kit Components:

  GA107746G1, ZHX1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107746G2, ZHX1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107746G3, ZHX1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001017926, NM_007222, NR_037873, NR_037874
• Synonyms: zinc-fingers and homeoboxes 1; zinc finger and homeodomain protein 1; zinc fingers and homeobox 1; zinc fingers and homeoboxes 1
• Summary: The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 1 of this gene family. In addition to forming homodimers, this protein heterodimerizes with members 2 and 3 of the zinc fingers and homeoboxes family. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream chromosome 8 open reading frame 76 (C8orf76) gene. [provided by RefSeq, Feb 2011]