Human HRH3 activation kit by CRISPRa

CAT#: GA107756

HRH3 CRISPRa kit - CRISPR gene activation of human histamine receptor H3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HRH3
• Locus ID: 11255
• Kit Components:

  GA107756G1, HRH3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107756G2, HRH3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107756G3, HRH3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_007232
• Synonyms: GPCR97; HH3R
• Summary: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system. [provided by RefSeq, Jul 2008]