Human TREX1 activation kit by CRISPRa

CAT#: GA107772

TREX1 CRISPRa kit - CRISPR gene activation of human three prime repair exonuclease 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TREX1
• Locus ID: 11277
• Kit Components:

  GA107772G1, TREX1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107772G2, TREX1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107772G3, TREX1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_007248, NM_016381, NM_033629, NM_033627, NM_033628
• Synonyms: AGS1; CRV; DRN3; HERNS
• Summary: This gene encodes a nuclear protein with 3' exonuclease activity. The encoded protein may play a role in DNA repair and serve as a proofreading function for DNA polymerase. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, Cree encephalitis, and other diseases of the immune system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012]