Human RBPSUHL (RBPJL) activation kit by CRISPRa

CAT#: GA107787

RBPJL CRISPRa kit - CRISPR gene activation of human recombination signal binding protein for immunoglobulin kappa J region like

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RBPJL
• Locus ID: 11317
• Kit Components:

  GA107787G1, RBPJL gRNA vector 1 in pCas-Guide-CRISPRa

  GA107787G2, RBPJL gRNA vector 2 in pCas-Guide-CRISPRa

  GA107787G3, RBPJL gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001281448, NM_001281449, NM_014276
• Synonyms: RBPL; RBPSUHL; SUHL
• Summary: This gene encodes a member of the suppressor of hairless protein family. A similar protein in mouse is a transcription factor that binds to DNA sequences almost identical to that bound by the Notch receptor signaling pathway transcription factor recombining binding protein J. The mouse protein has been shown to activate transcription in concert with Epstein-Barr virus nuclear antigen-2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]