Human GABARAP activation kit by CRISPRa

CAT#: GA107804

GABARAP CRISPRa kit - CRISPR gene activation of human GABA type A receptor-associated protein

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GABARAP
• Locus ID: 11337
• Kit Components:

  GA107804G1, GABARAP gRNA vector 1 in pCas-Guide-CRISPRa

  GA107804G2, GABARAP gRNA vector 2 in pCas-Guide-CRISPRa

  GA107804G3, GABARAP gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_007278
• Synonyms: ATG8A; GABARAP-a; MM46
• Summary: Gamma-aminobutyric acid A receptors [GABA(A) receptors] are ligand-gated chloride channels that mediate inhibitory neurotransmission. This gene encodes GABA(A) receptor-associated protein, which is highly positively charged in its N-terminus and shares sequence similarity with light chain-3 of microtubule-associated proteins 1A and 1B. This protein clusters neurotransmitter receptors by mediating interaction with the cytoskeleton. [provided by RefSeq, Jul 2008]