Human CASC3 activation kit by CRISPRa

CAT#: GA107814

CASC3 CRISPRa kit - CRISPR gene activation of human CASC3 exon junction complex subunit

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CASC3
• Locus ID: 22794
• Kit Components:

  GA107814G1, CASC3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107814G2, CASC3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107814G3, CASC3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_007359
• Synonyms: BTZ; MLN51
• Summary: The product of this gene is a core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated mRNA decay (NMD). The encoded protein binds RNA and interacts with two other EJC core components. It is predominantly located in the cytoplasm, but shuttles into the nucleus where it localizes to nuclear speckles. [provided by RefSeq, Jul 2008]