Human ZNFN1A2 (IKZF2) activation kit by CRISPRa

CAT#: GA107824

IKZF2 CRISPRa kit - CRISPR gene activation of human IKAROS family zinc finger 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IKZF2
• Locus ID: 22807
• Kit Components:

  GA107824G1, IKZF2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107824G2, IKZF2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107824G3, IKZF2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001079526, NM_016260
• Synonyms: ANF1A2; HELIOS; ZNF1A2; ZNFN1A2
• Summary: This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This protein forms homo- or hetero-dimers with other Ikaros family members, and is thought to function predominantly in early hematopoietic development. Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]