Human DLGAP4 activation kit by CRISPRa

CAT#: GA107844

DLGAP4 CRISPRa kit - CRISPR gene activation of human DLG associated protein 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DLGAP4
• Locus ID: 22839
• Kit Components:

  GA107844G1, DLGAP4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107844G2, DLGAP4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107844G3, DLGAP4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001042486, NM_014902, NM_183006, NM_001365621
• Synonyms: DAP-4; DAP4; DLP4; SAPAP-4; SAPAP4
• Summary: The product of this gene is a membrane-associated guanylate kinase found at the postsynaptic density in neuronal cells. It is a signaling molecule that can interact with potassium channels and receptors, as well as other signaling molecules. The protein encoded by this gene can interact with PSD-95 through its guanylate kinase domain and may be involved in clustering PSD-95 in the postsynaptic density region. The encoded protein is one of at least four similar proteins that have been found. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]