Human ICK activation kit by CRISPRa

CAT#: GA107858

ICK CRISPRa kit - CRISPR gene activation of human intestinal cell kinase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ICK
• Locus ID: 22858
• Kit Components:

  GA107858G1, ICK gRNA vector 1 in pCas-Guide-CRISPRa

  GA107858G2, ICK gRNA vector 2 in pCas-Guide-CRISPRa

  GA107858G3, ICK gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_014920, NM_016513, NM_173041
• Synonyms: ECO; LCK2; MRK
• Summary: Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. This gene encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. Alternative splicing has been observed at this locus and two variants, encoding the same isoform, have been identified. [provided by RefSeq, Jul 2008]