Human ARSG activation kit by CRISPRa

CAT#: GA107896

ARSG CRISPRa kit - CRISPR gene activation of human arylsulfatase G

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ARSG
• Locus ID: 22901
• Kit Components:

  GA107896G1, ARSG gRNA vector 1 in pCas-Guide-CRISPRa

  GA107896G2, ARSG gRNA vector 2 in pCas-Guide-CRISPRa

  GA107896G3, ARSG gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001267727, NM_014960, NM_001352899, NM_001352900, NM_001352901, NM_001352902, NM_001352903, NM_001352904, NM_001352905, NM_001352906, NM_001352907, NM_001352909, NM_001352910
• Summary: The protein encoded by this gene belongs to the sulfatase enzyme family. Sulfatases hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules. This protein displays arylsulfatase activity at acidic pH, as is typical of lysosomal sulfatases, and has been shown to localize in the lysosomes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012]