Human PLA2R (PLA2R1) activation kit by CRISPRa

CAT#: GA107916

PLA2R1 CRISPRa kit - CRISPR gene activation of human phospholipase A2 receptor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PLA2R1
• Locus ID: 22925
• Kit Components:

  GA107916G1, PLA2R1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107916G2, PLA2R1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107916G3, PLA2R1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001007267, NM_001195641, NM_007366
• Synonyms: CLEC13C; PLA2-R; PLA2G1R; PLA2IR; PLA2R
• Summary: This gene represents a phospholipase A2 receptor. The encoded protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. Polymorphisms at this locus have been associated with susceptibility to idiopathic membranous nephropathy. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Sep 2010]