Human RanBP16 (XPO7) activation kit by CRISPRa

CAT#: GA107991

XPO7 CRISPRa kit - CRISPR gene activation of human exportin 7

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: XPO7
• Locus ID: 23039
• Kit Components:

  GA107991G1, XPO7 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107991G2, XPO7 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107991G3, XPO7 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001100161, NM_001100162, NM_015024, NM_001362802, NR_156173
• Synonyms: exportin 7; KIAA0745; RAN binding protein 16; RANBP16
• Summary: The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-16 is a member of the importin-beta superfamily of nuclear transport receptors. [supplied by OMIM, Jul 2002]