Human FBP17 (FNBP1) activation kit by CRISPRa

CAT#: GA107998

FNBP1 CRISPRa kit - CRISPR gene activation of human formin binding protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FNBP1
• Locus ID: 23048
• Kit Components:

  GA107998G1, FNBP1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107998G2, FNBP1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107998G3, FNBP1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_015033, NM_001363755
• Synonyms: FBP17
• Summary: The protein encoded by this gene is a member of the formin-binding-protein family. The protein contains an N-terminal Fer/Cdc42-interacting protein 4 (CIP4) homology (FCH) domain followed by a coiled-coil domain, a proline-rich motif, a second coiled-coil domain, a Rho family protein-binding domain (RBD), and a C-terminal SH3 domain. This protein binds sorting nexin 2 (SNX2), tankyrase (TNKS), and dynamin; an interaction between this protein and formin has not been demonstrated yet in human. [provided by RefSeq, Jul 2008]