Human NMNAT2 activation kit by CRISPRa

CAT#: GA108004

NMNAT2 CRISPRa kit - CRISPR gene activation of human nicotinamide nucleotide adenylyltransferase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NMNAT2
• Locus ID: 23057
• Kit Components:

  GA108004G1, NMNAT2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108004G2, NMNAT2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108004G3, NMNAT2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_015039, NM_170706
• Synonyms: C1orf15; PNAT2
• Summary: This gene product belongs to the nicotinamide mononucleotide adenylyltransferase (NMNAT) enzyme family, members of which catalyze an essential step in NAD (NADP) biosynthetic pathway. Unlike the other human family member, which is localized to the nucleus, and is ubiquitously expressed; this enzyme is cytoplasmic, and is predominantly expressed in the brain. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]