Human CDC2L6 (CDK19) activation kit by CRISPRa

CAT#: GA108036

CDK19 CRISPRa kit - CRISPR gene activation of human cyclin dependent kinase 19

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CDK19
• Locus ID: 23097
• Kit Components:

  GA108036G1, CDK19 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108036G2, CDK19 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108036G3, CDK19 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001300960, NM_001300963, NM_001300964, NM_015076
• Synonyms: bA346C16.3; CDC2L6; CDK11
• Summary: This gene encodes a protein that is one of the components of the Mediator co-activator complex. The Mediator complex is a multi-protein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]