Human Septin 8 (SEPT8) activation kit by CRISPRa

CAT#: GA108098

SEPTIN8 CRISPRa kit - CRISPR gene activation of human septin 8

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SEPT8
• Locus ID: 23176
• Kit Components:

  GA108098G1, SEPT8 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108098G2, SEPT8 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108098G3, SEPT8 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001098811, NM_001098812, NM_001098813, NM_001300798, NM_001300799, NM_015146
• Synonyms: SEP2
• Summary: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]