Human PASK activation kit by CRISPRa

CAT#: GA108100

PASK CRISPRa kit - CRISPR gene activation of human PAS domain containing serine/threonine kinase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PASK
• Locus ID: 23178
• Kit Components:

  GA108100G1, PASK gRNA vector 1 in pCas-Guide-CRISPRa

  GA108100G2, PASK gRNA vector 2 in pCas-Guide-CRISPRa

  GA108100G3, PASK gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001252119, NM_001252120, NM_001252122, NM_001252124, NM_015148
• Synonyms: PASKIN; STK37
• Summary: This gene encodes a member of the serine/threonine kinase family that contains two PAS domains. Expression of this gene is regulated by glucose, and the encoded protein plays a role in the regulation of insulin gene expression. Downregulation of this gene may play a role in type 2 diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]