Human ARMER (ARL6IP1) activation kit by CRISPRa

CAT#: GA108122

ARL6IP1 CRISPRa kit - CRISPR gene activation of human ADP ribosylation factor like GTPase 6 interacting protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ARL6IP1
• Locus ID: 23204
• Kit Components:

  GA108122G1, ARL6IP1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108122G2, ARL6IP1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108122G3, ARL6IP1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001313858, NM_015161
• Synonyms: AIP1; ARL6IP; ARMER; SPG61
• Summary: This gene belongs to the ARL6ip family and encodes a transmembrane protein that is predominantly localized to intracytoplasmic membranes. It is highly expressed in early myeloid progenitor cells and thought to be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation. Mutations in this gene are associated with spastic paraplegia 61 (SPG61). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015]