Human SYT11 activation kit by CRISPRa

CAT#: GA108125

SYT11 CRISPRa kit - CRISPR gene activation of human synaptotagmin 11

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SYT11
• Locus ID: 23208
• Kit Components:

  GA108125G1, SYT11 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108125G2, SYT11 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108125G3, SYT11 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_152280
• Synonyms: SYT12; sytXI
• Summary: This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that are known calcium sensors and mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. The encoded protein is also a substrate for ubiquitin-E3-ligase parkin. The gene has previously been referred to as synaptotagmin XII but has been renamed synaptotagmin XI to be consistent with mouse and rat official nomenclature. [provided by RefSeq, Apr 2010]