Human JMJD6 activation kit by CRISPRa

CAT#: GA108127

JMJD6 CRISPRa kit - CRISPR gene activation of human jumonji domain containing 6, arginine demethylase and lysine hydroxylase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: JMJD6
• Locus ID: 23210
• Kit Components:

  GA108127G1, JMJD6 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108127G2, JMJD6 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108127G3, JMJD6 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001081461, NM_015167
• Synonyms: PSR; PTDSR; PTDSR1
• Summary: This gene encodes a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. This protein was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells; however, subsequent studies have indicated that it does not directly function in the clearance of apoptotic cells, and questioned whether it is a true phosphatidylserine receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]