Human Arg 3.1 (ARC) activation kit by CRISPRa

CAT#: GA108151

ARC CRISPRa kit - CRISPR gene activation of human activity regulated cytoskeleton associated protein

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ARC
• Locus ID: 23237
• Kit Components:

  GA108151G1, ARC gRNA vector 1 in pCas-Guide-CRISPRa

  GA108151G2, ARC gRNA vector 2 in pCas-Guide-CRISPRa

  GA108151G3, ARC gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_015193
• Synonyms: Arg3.1
• Summary: Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration. [UniProtKB/Swiss-Prot Function]