Human ACSL6 activation kit by CRISPRa

CAT#: GA108204

ACSL6 CRISPRa kit - CRISPR gene activation of human acyl-CoA synthetase long chain family member 6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ACSL6
• Locus ID: 23305
• Kit Components:

  GA108204G1, ACSL6 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108204G2, ACSL6 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108204G3, ACSL6 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001009185, NM_001205247, NM_001205248, NM_001205250, NM_001205251, NM_015256
• Synonyms: ACS2; FACL6; LACS2; LACS5; LACS 6
• Summary: The protein encoded by this gene catalyzes the formation of acyl-CoA from fatty acids, ATP, and CoA, using magnesium as a cofactor. The encoded protein plays a major role in fatty acid metabolism in the brain. Translocations with the ETV6 gene are causes of myelodysplastic syndrome with basophilia, acute myelogenous leukemia with eosinophilia, and acute eosinophilic leukemia. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2011]