Human CLASP1 activation kit by CRISPRa

CAT#: GA108226

CLASP1 CRISPRa kit - CRISPR gene activation of human cytoplasmic linker associated protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CLASP1
• Locus ID: 23332
• Kit Components:

  GA108226G1, CLASP1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108226G2, CLASP1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108226G3, CLASP1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001142273, NM_001142274, NM_001207051, NM_015282
• Synonyms: MAST1
• Summary: CLASPs, such as CLASP1, are nonmotor microtubule-associated proteins that interact with CLIPs (e.g., CLIP170; MIM 179838). CLASP1 is involved in the regulation of microtubule dynamics at the kinetochore and throughout the spindle (Maiato et al., 2003 [PubMed 12837247]). [supplied by OMIM, Mar 2008]