Human Desmuslin (SYNM) activation kit by CRISPRa

CAT#: GA108230

SYNM CRISPRa kit - CRISPR gene activation of human synemin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SYNM
• Locus ID: 23336
• Kit Components:

  GA108230G1, SYNM gRNA vector 1 in pCas-Guide-CRISPRa

  GA108230G2, SYNM gRNA vector 2 in pCas-Guide-CRISPRa

  GA108230G3, SYNM gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_015286, NM_145728
• Synonyms: DMN; SYN
• Summary: The protein encoded by this gene is an intermediate filament (IF) family member. IF proteins are cytoskeletal proteins that confer resistance to mechanical stress and are encoded by a dispersed multigene family. This protein has been found to form a linkage between desmin, which is a subunit of the IF network, and the extracellular matrix, and provides an important structural support in muscle. Two alternatively spliced variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]