Human Nesprin 1 (SYNE1) activation kit by CRISPRa

CAT#: GA108235

SYNE1 CRISPRa kit - CRISPR gene activation of human spectrin repeat containing nuclear envelope protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SYNE1
• Locus ID: 23345
• Kit Components:

  GA108235G1, SYNE1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108235G2, SYNE1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108235G3, SYNE1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_015293, NM_033071, NM_133650, NM_182961, NM_001347701, NM_001347702
• Synonyms: 8B; ARCA1; C6orf98; CPG2; dJ45H2.2; DKFZp781J13156; EDMD4; FLJ30878; FLJ41140; KIAA0796
• Summary: This gene encodes a spectrin repeat containing protein expressed in skeletal and smooth muscle, and peripheral blood lymphocytes, that localizes to the nuclear membrane. Mutations in this gene have been associated with autosomal recessive spinocerebellar ataxia 8, also referred to as autosomal recessive cerebellar ataxia type 1 or recessive ataxia of Beauce. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]