Human ASPP1 (PPP1R13B) activation kit by CRISPRa

CAT#: GA108255

PPP1R13B CRISPRa kit - CRISPR gene activation of human protein phosphatase 1 regulatory subunit 13B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PPP1R13B
• Locus ID: 23368
• Kit Components:

  GA108255G1, PPP1R13B gRNA vector 1 in pCas-Guide-CRISPRa

  GA108255G2, PPP1R13B gRNA vector 2 in pCas-Guide-CRISPRa

  GA108255G3, PPP1R13B gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_015316
• Synonyms: ASPP1; p53BP2-like; p85
• Summary: This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor. [provided by RefSeq, Jul 2008]