Human SRGAP2 activation kit by CRISPRa

CAT#: GA108263

SRGAP2 CRISPRa kit - CRISPR gene activation of human SLIT-ROBO Rho GTPase activating protein 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SRGAP2
• Locus ID: 23380
• Kit Components:

  GA108263G1, SRGAP2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108263G2, SRGAP2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108263G3, SRGAP2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001042758, NM_001170637, NM_001300952, NM_015326
• Synonyms: ARHGAP34; FNBP2; SRGAP2A; SRGAP3
• Summary: This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting from segmental duplication. While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Jul 2014]