Human SPECC1L activation kit by CRISPRa

CAT#: GA108267

SPECC1L CRISPRa kit - CRISPR gene activation of human sperm antigen with calponin homology and coiled-coil domains 1 like

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SPECC1L
• Locus ID: 23384
• Kit Components:

  GA108267G1, SPECC1L gRNA vector 1 in pCas-Guide-CRISPRa

  GA108267G2, SPECC1L gRNA vector 2 in pCas-Guide-CRISPRa

  GA108267G3, SPECC1L gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001145468, NM_001254732, NM_001254733, NM_015330
• Synonyms: CYTSA; GBBB2; OBLFC1
• Summary: This gene encodes a coiled-coil domain containing protein. The encoded protein may play a critical role in actin-cytoskeletal reorganization during facial morphogenesis. Mutations in this gene are a cause of oblique facial clefting-1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A read-through transcript composed of SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and the downstream ADORA2A (adenosine A2a receptor) gene sequence has been identified, but it is thought to be non-coding. [provided by RefSeq, Jun 2013]