Human PIP5KI gamma (PIP5K1C) activation kit by CRISPRa

CAT#: GA108276

PIP5K1C CRISPRa kit - CRISPR gene activation of human phosphatidylinositol-4-phosphate 5-kinase type 1 gamma

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PIP5K1C
• Locus ID: 23396
• Kit Components:

  GA108276G1, PIP5K1C gRNA vector 1 in pCas-Guide-CRISPRa

  GA108276G2, PIP5K1C gRNA vector 2 in pCas-Guide-CRISPRa

  GA108276G3, PIP5K1C gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001195733, NM_001300849, NM_012398
• Synonyms: LCCS3; PIP5K-GAMMA; PIP5K1-gamma; PIP5Kgamma
• Summary: This locus encodes a type I phosphatidylinositol 4-phosphate 5-kinase. The encoded protein catalyzes phosphorylation of phosphatidylinositol 4-phosphate, producing phosphatidylinositol 4,5-bisphosphate. This enzyme is found at synapses and has been found to play roles in endocytosis and cell migration. Mutations at this locus have been associated with lethal congenital contractural syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Sep 2010]