Human BRRN1 (NCAPH) activation kit by CRISPRa

CAT#: GA108277

NCAPH CRISPRa kit - CRISPR gene activation of human non-SMC condensin I complex subunit H

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NCAPH
• Locus ID: 23397
• Kit Components:

  GA108277G1, NCAPH gRNA vector 1 in pCas-Guide-CRISPRa

  GA108277G2, NCAPH gRNA vector 2 in pCas-Guide-CRISPRa

  GA108277G3, NCAPH gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001281710, NM_001281711, NM_001281712, NM_015341
• Synonyms: BRRN1; CAP-H
• Summary: This gene encodes a member of the barr gene family and a regulatory subunit of the condensin complex. This complex is required for the conversion of interphase chromatin into condensed chromosomes. The protein encoded by this gene is associated with mitotic chromosomes, except during the early phase of chromosome condensation. During interphase, the protein has a distinct punctate nucleolar localization. Alternatively spliced transcript variants encoding different proteins have been described. [provided by RefSeq, Jul 2013]