Human FOG2 (ZFPM2) activation kit by CRISPRa

CAT#: GA108292

ZFPM2 CRISPRa kit - CRISPR gene activation of human zinc finger protein, FOG family member 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ZFPM2
• Locus ID: 23414
• Kit Components:

  GA108292G1, ZFPM2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108292G2, ZFPM2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108292G3, ZFPM2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_012082, NM_001362836, NM_001362837
• Synonyms: DIH3; FOG2; hFOG-2; SRXY9; ZC2HC11B; ZNF89B
• Summary: The zinc finger protein encoded by this gene is a widely expressed member of the FOG family of transcription factors. The family members modulate the activity of GATA family proteins, which are important regulators of hematopoiesis and cardiogenesis in mammals. It has been demonstrated that the protein can both activate and down-regulate expression of GATA-target genes, suggesting different modulation in different promoter contexts. A related mRNA suggests an alternatively spliced product but this information is not yet fully supported by the sequence. [provided by RefSeq, Jul 2008]