Human KCNH4 activation kit by CRISPRa

CAT#: GA108293

KCNH4 CRISPRa kit - CRISPR gene activation of human potassium voltage-gated channel subfamily H member 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KCNH4
• Locus ID: 23415
• Kit Components:

  GA108293G1, KCNH4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108293G2, KCNH4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108293G3, KCNH4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_012285
• Synonyms: BEC2; ELK1; Kv12.3
• Summary: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. The gene is brain-specific, and located in the neocortex and the striatum. It may be involved in cellular excitability of restricted neurons in the central nervous system. [provided by RefSeq, Jul 2008]