Human MLYCD activation kit by CRISPRa

CAT#: GA108295

MLYCD CRISPRa kit - CRISPR gene activation of human malonyl-CoA decarboxylase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MLYCD
• Locus ID: 23417
• Kit Components:

  GA108295G1, MLYCD gRNA vector 1 in pCas-Guide-CRISPRa

  GA108295G2, MLYCD gRNA vector 2 in pCas-Guide-CRISPRa

  GA108295G3, MLYCD gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_012213
• Synonyms: MCD
• Summary: The product of this gene catalyzes the breakdown of malonyl-CoA to acetyl-CoA and carbon dioxide. Malonyl-CoA is an intermediate in fatty acid biosynthesis, and also inhibits the transport of fatty acyl CoAs into mitochondria. Consequently, the encoded protein acts to increase the rate of fatty acid oxidation. It is found in mitochondria, peroxisomes, and the cytoplasm. Mutations in this gene result in malonyl-CoA decarboyxlase deficiency. [provided by RefSeq, Jul 2008]