Human ABCB9 activation kit by CRISPRa

CAT#: GA108319

ABCB9 CRISPRa kit - CRISPR gene activation of human ATP binding cassette subfamily B member 9

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ABCB9
• Locus ID: 23457
• Kit Components:

  GA108319G1, ABCB9 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108319G2, ABCB9 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108319G3, ABCB9 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001243013, NM_001243014, NM_019624, NM_019625, NM_203444, NM_203445
• Synonyms: EST122234; TAPL
• Summary: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This family member functions in the translocation of peptides from the cytosol into the lysosomal lumen. Alternative splicing of this gene results in distinct isoforms which are likely to have different substrate specificities. [provided by RefSeq, Jul 2011]