Human CMT (ICMT) activation kit by CRISPRa

CAT#: GA108323

ICMT CRISPRa kit - CRISPR gene activation of human isoprenylcysteine carboxyl methyltransferase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ICMT
• Locus ID: 23463
• Kit Components:

  GA108323G1, ICMT gRNA vector 1 in pCas-Guide-CRISPRa

  GA108323G2, ICMT gRNA vector 2 in pCas-Guide-CRISPRa

  GA108323G3, ICMT gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_012405, NM_170705
• Synonyms: HSTE14; MST098; MSTP098; PCCMT; PCMT; PPMT
• Summary: This gene encodes the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined. [provided by RefSeq, Jul 2008]