Human SEC11A activation kit by CRISPRa

CAT#: GA108334

SEC11A CRISPRa kit - CRISPR gene activation of human SEC11 homolog A, signal peptidase complex subunit

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SEC11A
• Locus ID: 23478
• Kit Components:

  GA108334G1, SEC11A gRNA vector 1 in pCas-Guide-CRISPRa

  GA108334G2, SEC11A gRNA vector 2 in pCas-Guide-CRISPRa

  GA108334G3, SEC11A gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001271918, NM_001271919, NM_001271920, NM_001271921, NM_001271922, NM_014300, NR_073518
• Synonyms: 1810012E07Rik; SEC11L1; sid2895; SPC18; SPCS4A
• Summary: This gene encodes a member of the peptidase S26B family. The encoded protein is an 18kDa subunit of the signal peptidase complex and has been linked to cell migration and invasion, gastric cancer and lymph node metastasis. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8. [provided by RefSeq, Dec 2012]