Human TACI (TNFRSF13B) activation kit by CRISPRa

CAT#: GA108343

TNFRSF13B CRISPRa kit - CRISPR gene activation of human TNF receptor superfamily member 13B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TNFRSF13B
• Locus ID: 23495
• Kit Components:

  GA108343G1, TNFRSF13B gRNA vector 1 in pCas-Guide-CRISPRa

  GA108343G2, TNFRSF13B gRNA vector 2 in pCas-Guide-CRISPRa

  GA108343G3, TNFRSF13B gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_012452
• Synonyms: CD267; CVID; CVID2; IGAD2; RYZN; TACI; TNFRSF14B
• Summary: The protein encoded by this gene is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]