Human CAIN (CABIN1) activation kit by CRISPRa

CAT#: GA108367

CABIN1 CRISPRa kit - CRISPR gene activation of human calcineurin binding protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CABIN1
• Locus ID: 23523
• Kit Components:

  GA108367G1, CABIN1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108367G2, CABIN1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108367G3, CABIN1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001199281, NM_001201429, NM_012295
• Synonyms: CAIN; KB-318B8.7; PPP3IN
• Summary: Calcineurin plays an important role in the T-cell receptor-mediated signal transduction pathway. The protein encoded by this gene binds specifically to the activated form of calcineurin and inhibits calcineurin-mediated signal transduction. The encoded protein is found in the nucleus and contains a leucine zipper domain as well as several PEST motifs, sequences which confer targeted degradation to those proteins which contain them. Alternative splicing results in multiple transcript variants encoding two different isoforms. [provided by RefSeq, Jan 2011]