Human NNT activation kit by CRISPRa

CAT#: GA108373

NNT CRISPRa kit - CRISPR gene activation of human nicotinamide nucleotide transhydrogenase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NNT
• Locus ID: 23530
• Kit Components:

  GA108373G1, NNT gRNA vector 1 in pCas-Guide-CRISPRa

  GA108373G2, NNT gRNA vector 2 in pCas-Guide-CRISPRa

  GA108373G3, NNT gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001331026, NM_012343, NM_182977
• Synonyms: GCCD4
• Summary: This gene encodes an integral protein of the inner mitochondrial membrane. The enzyme couples hydride transfer between NAD(H) and NADP(+) to proton translocation across the inner mitochondrial membrane. Under most physiological conditions, the enzyme uses energy from the mitochondrial proton gradient to produce high concentrations of NADPH. The resulting NADPH is used for biosynthesis and in free radical detoxification. [provided by RefSeq, Sep 2016]