Human PIGN activation kit by CRISPRa

CAT#: GA108396

PIGN CRISPRa kit - CRISPR gene activation of human phosphatidylinositol glycan anchor biosynthesis class N

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PIGN
• Locus ID: 23556
• Kit Components:

  GA108396G1, PIGN gRNA vector 1 in pCas-Guide-CRISPRa

  GA108396G2, PIGN gRNA vector 2 in pCas-Guide-CRISPRa

  GA108396G3, PIGN gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_012327, NM_176787
• Synonyms: MCAHS; MCAHS1; MCD4; MDC4; PIG-N
• Summary: This gene encodes a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is expressed in the endoplasmic reticulum and transfers phosphoethanolamine (EtNP) to the first mannose of the GPI anchor. Two alternatively spliced variants, which encode an identical isoform, have been reported. [provided by RefSeq, Jul 2008]