Human WBP2 activation kit by CRISPRa

CAT#: GA108398

WBP2 CRISPRa kit - CRISPR gene activation of human WW domain binding protein 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: WBP2
• Locus ID: 23558
• Kit Components:

  GA108398G1, WBP2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108398G2, WBP2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108398G3, WBP2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_012478, NM_001330499, NM_001348170
• Synonyms: WBP-2
• Summary: The globular WW domain is composed of 38 to 40 semiconserved amino acids shared by proteins of diverse functions including structural, regulatory, and signaling proteins. The domain is involved in mediating protein-protein interactions through the binding of polyproline ligands. This gene encodes a WW domain binding protein that is a transcriptional coactivator of estrogen receptor alpha and progesterone receptor. Defects in this gene have been associated with hearing impairment. [provided by RefSeq, Jan 2017]