Human DDX58 activation kit by CRISPRa

CAT#: GA108415

DDX58 CRISPRa kit - CRISPR gene activation of human DExD/H-box helicase 58

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DDX58
• Locus ID: 23586
• Kit Components:

  GA108415G1, DDX58 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108415G2, DDX58 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108415G3, DDX58 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_014314
• Synonyms: RIG-I; RIGI; RLR-1
• Summary: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of immune response. [provided by RefSeq, Jul 2008]