Human HEBP2 activation kit by CRISPRa

CAT#: GA108421

HEBP2 CRISPRa kit - CRISPR gene activation of human heme binding protein 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HEBP2
• Locus ID: 23593
• Kit Components:

  GA108421G1, HEBP2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108421G2, HEBP2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108421G3, HEBP2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_014320, NM_001326380, NM_001326381
• Synonyms: C6orf34; C6ORF34B; PP23; SOUL
• Summary: The protein encoded by this gene is found predominately in the cytoplasm, where it plays a role in the collapse of mitochondrial membrane potential (MMP) prior to necrotic cell death. The encoded protein enhances outer and inner mitochondrial membrane permeabilization, especially under conditions of oxidative stress. [provided by RefSeq, May 2016]