Human MD2 (LY96) activation kit by CRISPRa

CAT#: GA108455

LY96 CRISPRa kit - CRISPR gene activation of human lymphocyte antigen 96

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: LY96
• Locus ID: 23643
• Kit Components:

  GA108455G1, LY96 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108455G2, LY96 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108455G3, LY96 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001195797, NM_015364
• Synonyms: ESOP-1; ly-96; MD-2; MD2
• Summary: This gene encodes a protein which associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccyaride (LPS), thus providing a link between the receptor and LPS signaling. Studies of the mouse ortholog suggest that this gene may be involved in endotoxin neutralization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2010]