Human GADD34 (PPP1R15A) activation kit by CRISPRa

CAT#: GA108457

PPP1R15A CRISPRa kit - CRISPR gene activation of human protein phosphatase 1 regulatory subunit 15A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PPP1R15A
• Locus ID: 23645
• Kit Components:

  GA108457G1, PPP1R15A gRNA vector 1 in pCas-Guide-CRISPRa

  GA108457G2, PPP1R15A gRNA vector 2 in pCas-Guide-CRISPRa

  GA108457G3, PPP1R15A gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_014330
• Synonyms: GADD34
• Summary: This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation. [provided by RefSeq, Jul 2008]