Human SH3BP4 activation kit by CRISPRa

CAT#: GA108472

SH3BP4 CRISPRa kit - CRISPR gene activation of human SH3 domain binding protein 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SH3BP4
• Locus ID: 23677
• Kit Components:

  GA108472G1, SH3BP4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108472G2, SH3BP4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108472G3, SH3BP4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_014521
• Synonyms: BOG25; TTP
• Summary: This gene encodes a protein with 3 Asn-Pro-Phe (NPF) motifs, an SH3 domain, a PXXP motif, a bipartite nuclear targeting signal, and a tyrosine phosphorylation site. This protein is involved in cargo-specific control of clathrin-mediated endocytosis, specifically controlling the internalization of a specific protein receptor. [provided by RefSeq, Jul 2008]