Human PGEA1 (CBY1) activation kit by CRISPRa

CAT#: GA108529

CBY1 CRISPRa kit - CRISPR gene activation of human chibby family member 1, beta catenin antagonist


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol CBY1
Locus ID 25776
Kit Components

GA108529G1, CBY1 gRNA vector 1 in pCas-Guide-CRISPRa

GA108529G2, CBY1 gRNA vector 2 in pCas-Guide-CRISPRa

GA108529G3, CBY1 gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001002880, NM_015373
Synonyms arb1; C22orf2; CBY; HS508I15A; PGEA1; PIGEA-14; PIGEA14
Summary Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.