Human QPCT activation kit by CRISPRa

CAT#: GA108542

QPCT CRISPRa kit - CRISPR gene activation of human glutaminyl-peptide cyclotransferase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: QPCT
• Locus ID: 25797
• Kit Components:

  GA108542G1, QPCT gRNA vector 1 in pCas-Guide-CRISPRa

  GA108542G2, QPCT gRNA vector 2 in pCas-Guide-CRISPRa

  GA108542G3, QPCT gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_012413
• Synonyms: GCT; QC; sQC
• Summary: This gene encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86% identical to that of bovine glutaminyl cyclase. [provided by RefSeq, Jul 2008]