Human ATXN10 activation kit by CRISPRa

CAT#: GA108555

ATXN10 CRISPRa kit - CRISPR gene activation of human ataxin 10

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ATXN10
• Locus ID: 25814
• Kit Components:

  GA108555G1, ATXN10 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108555G2, ATXN10 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108555G3, ATXN10 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001167621, NM_013236
• Synonyms: E46L; HUMEEP; SCA10
• Summary: This gene encodes a protein that may function in neuron survival, neuron differentiation, and neuritogenesis. These roles may be carried out via activation of the mitogen-activated protein kinase cascade. Expansion of an ATTCT repeat from 9-32 copies to 800-4500 copies in an intronic region of this locus has been associated with spinocerebellar ataxia, type 10. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2016]