Human BACE2 activation kit by CRISPRa
CAT#: GA108565
BACE2 CRISPRa kit - CRISPR gene activation of human beta-secretase 2
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | BACE2 |
Locus ID | 25825 |
Kit Components | GA108565G1, BACE2 gRNA vector 1 in pCas-Guide-CRISPRa GA108565G2, BACE2 gRNA vector 2 in pCas-Guide-CRISPRa GA108565G3, BACE2 gRNA vector 3 in pCas-Guide-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100058 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_012105, NM_138991, NM_138992 |
Synonyms | AEPLC; ALP56; ASP1; ASP21; BAE2; CDA13; CEAP1; DRAP |
Summary | This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN404860 | BACE2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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